暴露于生長因子豐富的環(huán)境對器官疾病、組織損傷的再生,例如骨骼系統(tǒng)缺陷和骨再生具有顯著的恢復(fù)作用。盡管已經(jīng)有研究報道了將某些生長因子引入相關(guān)領(lǐng)域,但是它們的再生效果不令人滿意。最近,華東理工大學(xué)在期刊《Bioactive Materials》(IF=16.874)上發(fā)表題為 “Recapitulation of growth factor-enriched microenvironment via BMP receptor activating hydrogel.” 的文章,研究出一個生長因子富集的微環(huán)境(GEM)的創(chuàng)新水凝膠。這種硫酸化水凝膠包含了骨形態(tài)發(fā)生蛋白-2 (BMP-2),這是成骨過程中的一種重要生長因子,可指導(dǎo)間充質(zhì)干細胞(MSC)分化,刺激細胞增殖,并改善骨形成。半合成水凝膠磺化明膠(S-Gelatin)可以通過增強BMP-2和BMP-2 II型受體(BMPR2)之間的結(jié)合來放大小鼠MSCs中的BMP-2信號,這些受體位于MSC細胞核上并被水凝膠激活。研究結(jié)果顯示MSCs在整個再生過程中細胞因子分泌的顯著改善證實了S-Gelatin/rhBMP-2水凝膠獲得生長因子的潛力,促進血管形成。這個研究成果提供了一種新的策略,通過放大rhBMP-2的再生能力和捕獲內(nèi)源性生長因子來實現(xiàn)原位GEM和加速骨再生。
本文中使用了欣博盛Human BMP-2 ELISA kit檢測了材料中釋放的BMP-2的表達量。
1.文章題目:Recapitulation of growth factor-enriched microenvironment via BMP receptor activating hydrogel.
期 刊:Bioactive Materials(影響因子:16.874)
發(fā)表時間:1 July 2022
作 者:Zhang Q, Liu Y, Li J, et al.
作者單位:華東理工大學(xué)
使用產(chǎn)品:Human BMP-2 ELISA kit
https://pubmed.ncbi.nlm.nih.gov/35846838/
2.文章題目:Excessive IL-10 and IL-18 Trigger HLH-Like Hyperinflammation and Enhanced Myelopoiesis.
期 刊:Journal of Allergy and Clinical Immunology(影響因子:14.29)
發(fā)表時間:2 July 2022
作 者:Tang Y, Xu Q, Luo H, et al.
作者單位:華中科技大學(xué)同濟醫(yī)學(xué)院
使用產(chǎn)品:Human IL-10, IL-18, IL-2Ra ELISA kits
https://pubmed.ncbi.nlm.nih.gov/35792218/
3.文章題目:Homocysteine-targeting compounds as a new treatment strategy for diabetic wounds via inhibition of the histone methyltransferase SET7/9.
期 刊:Experimental & Molecular Medicine(影響因子:12.153)
發(fā)表時間:20 July 2022
作 者:Li G, Li D, Wu C, et al.
作者單位:澳門大學(xué)
使用產(chǎn)品:Human VEGF ELISA kit
https://pubmed.ncbi.nlm.nih.gov/35859119/
4.文章題目:Severe inflammation in new-borns induces long-term cognitive impairment by activation of IL-1β/KCC2 signaling during early development.
期 刊:BMC medicine(影響因子:11.15)
發(fā)表時間:27 July 2022
作 者:Zhang D, Yang Y, Yang Y, et al.
作者單位:四川大學(xué)華西醫(yī)院
使用產(chǎn)品:Rat TNF-α, IL-1β and IL-6 ELISA kits
https://pubmed.ncbi.nlm.nih.gov/35883093/
5.文章題目:cGAS inhibition alleviates Alu RNA-induced immune responses and cytotoxicity in retinal pigmented epithelium.
期 刊:Cell & Bioscience(影響因子:9.584)
發(fā)表時間:25 July 2022
作 者:Li J, Zhang F, Bian W, et al.
作者單位:首都醫(yī)科大學(xué)附屬北京同仁醫(yī)院
使用產(chǎn)品:Human IFN-β ELISA kit
https://pubmed.ncbi.nlm.nih.gov/35879806/
6.文章題目:Artificial stem cells mediated inflammation-tropic delivery of antiviral drugs for pneumonia treatment.
期 刊:Journal of Nanobiotechnology(影響因子:9.429)
發(fā)表時間:16 July 2022
作 者:Qin A, Chen S, Li S, et al.
作者單位:廣州醫(yī)科大學(xué)
使用產(chǎn)品:Mouse TNF-α, IL-6 ELISA kits
樣本類型:肺組織
https://pubmed.ncbi.nlm.nih.gov/35842662/
7.文章題目:Development of a risk nomogram model for identifying interstitial lung disease in patients with rheumatoid arthritis.
期 刊:Frontiers in Immunology(影響因子:8.786)
發(fā)表時間:1 July 2022
作 者:Xue J, Hu W, Wu S, et al.
作者單位:寧夏大學(xué)
使用產(chǎn)品:Human MMP-3 ELISA kit
https://pubmed.ncbi.nlm.nih.gov/35784288/
8.文章題目:Oncolytic adenovirus promotes vascular normalization and nonclassical tertiary lymphoid structure formation through STING-mediated DC activation.
期 刊:Oncoimmunology(影響因子:7.723)
發(fā)表時間:1 July 2022
作 者:He T, Hao Z, Lin M, et al.
作者單位:浙江大學(xué)
使用產(chǎn)品:Mouse IL-15 ELISA kit
https://pubmed.ncbi.nlm.nih.gov/35800155/
9.文章題目:Two Laminaria japonica polysaccharides with distinct structure characterization affect gut microbiota and metabolites in hyperlipidemic mice differently.
期 刊:Food Research International(影響因子:7.425)
發(fā)表時間:1 July 2022
作 者:Fang F, Xiao C, Wan C, et al.
作者單位:廣西大學(xué)輕工與食品工程學(xué)院
使用產(chǎn)品:Mouse TNF-α, IL-6 ELISA kits
樣本類型:肝組織
https://www.sciencedirect.com/science/article/abs/pii/S0963996922006731
10.文章題目:Bacillus cereus cytotoxin K triggers gasdermin D-dependent pyroptosis.
期 刊:Cell Death Discovery(影響因子:7.109)
發(fā)表時間:4 July 2022
作 者:Zhao Y, Sun L.
作者單位:中國科學(xué)院海洋大科學(xué)中心海洋研究所
使用產(chǎn)品:Human IL-1β ELISA kit
https://pubmed.ncbi.nlm.nih.gov/35788609/
11.文章題目:MicroRNA-193a-5p Rescues Ischemic Cerebral Injury by Restoring N2-Like Neutrophil Subsets.
期 刊:Translational Stroke Research(影響因子:6.8)
發(fā)表時間:29 July 2022
作 者:Han Z, Li L, Zhao H, et al.
作者單位:首都醫(yī)科大學(xué)
使用產(chǎn)品:Mouse TGF-β, TNF-α, IL-10 and IL-1β ELISA kits
樣本類型:大腦組織
https://pubmed.ncbi.nlm.nih.gov/35906328/
12.文章題目:DiHuangYin Decoction protects dopaminergic neurons in a Parkinson's disease model by alleviating peripheral inflammation.
期 刊:Phytomedicine(影響因子:6.656)
發(fā)表時間:24 July 2022
作 者:Wu Y, Liu H, Wang Y, et al.
作者單位:浙江大學(xué)藥學(xué)院藥物信息學(xué)研究所
使用產(chǎn)品:Mouse IL-6, IL-17A, IL-1βELISA kits
https://www.sciencedirect.com/science/article/pii/S0944711322004366
13.文章題目:A Novel Polysaccharide From Chuanminshen violaceum and Its Protective Effect Against Myocardial Injury.
期 刊:Frontiers in Nutrition(影響因子:6.59)
發(fā)表時間:14 July 2022
作 者:He P, Zhang M, Zhao M, et al.
作者單位:青島大學(xué)
使用產(chǎn)品:Mouse TNF-α, IL-6 ELISA kits
https://static.frontiersin.org/articles/10.3389/fnut.2022.961182/full
14.文章題目:Anti-inflammatory activity of flavonols via inhibiting MAPK and NF-κB signaling pathways in RAW264. 7 macrophages.
期 刊:Current Research in Food Science(影響因子:6.269)
發(fā)表時間:13 July 2022
作 者:Zhong R, Miao L, Zhang H, et al.
作者單位:澳門大學(xué)
使用產(chǎn)品:Mouse IL-6 and TNF-α ELISA kits
https://www.sciencedirect.com/science/article/pii/S2665927122001083
15.文章題目:Local and systemic inflammation triggers different outcomes of tumor growth related to infiltration of anti-tumor or pro-tumor macrophages.
期 刊:Chinese Medical Journal(影響因子:6.133)
發(fā)表時間:29 July 2022
作 者:Liu X, Jiang Q, Shen S, et al.
作者單位:南京大學(xué)醫(yī)學(xué)院
使用產(chǎn)品:Mouse IL-6, IL-1β ELISA kits
https://pubmed.ncbi.nlm.nih.gov/35903953/
16.文章題目:Gut Commensal Fungi Protect Against Acetaminophen-Induced Hepatotoxicity by Reducing Cyp2a5 Expression in Mice.
期 刊: Frontiers in Microbiology(影響因子:6.064)
發(fā)表時間:12 July 2022
作 者:He Z, Zeng Y, Li S, et al.
作者單位:南方醫(yī)科大學(xué)第三附屬醫(yī)院
使用產(chǎn)品:Mouse TNF-α, IL-6 and MCP-1 ELISA kits
https://static.frontiersin.org/articles/10.3389/fmicb.2022.944416/full
17.文章題目:A Novel In Vitro Platform Development in the Lab for Modeling Blast Injury to Microglia.
期 刊:Frontiers in Bioengineering and Biotechnology(影響因子:6.064)
發(fā)表時間:12 July 2022
作 者:Xu D, Zhang N, Wang S, et al.
作者單位:西北工業(yè)大學(xué)
使用產(chǎn)品:Mouse TNF-α ELISA kit
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9315251/
18.文章題目:Magnetic Resonance Imaging Investigation of Neuroplasticity After Ischemic Stroke in Tetramethylpyrazine-Treated Rats.
期 刊:Frontiers in pharmacology(影響因子:5.988)
發(fā)表時間:1 July 2022
作 者:Feng X F, Lei J F, Li M Z, et al.
作者單位:首都醫(yī)科大學(xué)
使用產(chǎn)品:Anti-mouse IgG (H + L)-HRP antibody
https://pubmed.ncbi.nlm.nih.gov/35559236/
19.文章題目:Dao-Chi Powder Ameliorates Pancreatitis-Induced Intestinal and Cardiac Injuries via Regulating the Nrf2-HO-1-HMGB1 Signaling Pathway in Rats.
期 刊:Frontiers in Pharmacology(影響因子:5.988)
發(fā)表時間:11 July 2022
作 者:Yao J, Miao Y, Zhang Y, et al.
作者單位:四川大學(xué)華西醫(yī)院
使用產(chǎn)品:Rat IL-6, IL-10 ELISA kits
https://pubmed.ncbi.nlm.nih.gov/35899121/
20.文章題目:Dasatinib and interferon alpha synergistically induce pyroptosis-like cell death in philadelphia chromosome positive acute lymphoblastic leukemia.
期 刊: American Journal of Cancer Research(影響因子:5.942)
發(fā)表時間:1 July 2022
作 者:Dai Y, Huang J, Kuang P, et al.
作者單位:四川大學(xué)華西醫(yī)院
使用產(chǎn)品:Human IL-1β ELISA kit
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9251703/
21.文章題目:Zoledronic acid enhances the efficacy of immunotherapy in non-small cell lung cancer.
期 刊:International Immunopharmacology(影響因子:5.714)
發(fā)表時間:2 July 2022
作 者:Zheng Y, Wang P, Fu Y, et al.
作者單位:四川大學(xué)華西醫(yī)學(xué)院
使用產(chǎn)品:Mouse IL-18 ELISA kit
https://www.sciencedirect.com/science/article/pii/S1567576922005148
22.文章題目:Characterization of Purified Mulberry Leaf Glycoprotein and Its Immunoregulatory Effect on Cyclophosphamide-Treated Mice.
期 刊: Foods(影響因子:5.561)
發(fā)表時間:9 July 2022
作 者:Shan Y, Sun C, Li J, et al.
作者單位:暨南大學(xué)
使用產(chǎn)品:Mouse IL-2, IL-6, TNF-α, IgA, IgG ELISA kits
https://www.mdpi.com/2304-8158/11/14/2034
23.文章題目:Nobiletin Attenuates Anesthesia/Surgery-Induced Neurocognitive Decline by Preserving the Expression of Clock Genes in Mice.
期 刊:Frontiers in Neuroscience(影響因子:5.152)
發(fā)表時間:7 July 2022
作 者:Sun Z, Yang N, Jia X, et al.
作者單位:北京大學(xué)第三醫(yī)院
使用產(chǎn)品:Mouse IL-1β, IL-6, TNF-α ELISA kits
樣本類型:大腦海馬組織與前額葉皮層組織
https://pubmed.ncbi.nlm.nih.gov/35873828/
24.文章題目:Human Neutrophil Defensins Disrupt Liver Interendothelial Junctions and Aggravate Sepsis.
期 刊:Mediators of Inflammation(影響因子:4.529)
發(fā)表時間:7 July 2022
作 者:Chen Q X, Yang Y, Pan Y H, et al.
作者單位:浙江大學(xué)醫(yī)學(xué)院附屬兒童醫(yī)院
使用產(chǎn)品:Mouse IL-1β, IL-6 ELISA kits
https://www.hindawi.com/journals/mi/2022/7659282/
25.文章題目:WKYMVm/FPR2 Alleviates Spinal Cord Injury by Attenuating the Inflammatory Response of Microglia.
期 刊:Mediators of Inflammation(影響因子:4.529)
發(fā)表時間:11 July 2022
作 者:Zhang W, Chen J, Guo W, et al.
作者單位:中山大學(xué)附屬第一醫(yī)院
使用產(chǎn)品:Rat TNF-α, IL-6, and IL-1βELISA kits
https://www.hindawi.com/journals/mi/2022/4408099/
26.文章題目:Combined inhibition of BADSer99 phosphorylation and PARP ablates models of recurrent ovarian carcinoma.
期 刊:Communications Medicine(影響因子:4.5)
發(fā)表時間:2 July 2022
作 者:Zhang X, Wang L, Chen S, et al.
作者單位:深圳灣實驗室
使用產(chǎn)品:Annexin V-FITC/PI apoptosis assay kit
https://www.nature.com/articles/s43856-022-00142-3
27.文章題目:β-sitosterol inhibits ovalbumin-induced asthma-related inflammation by regulating dendritic cells.
期 刊:Immunopharmacology and Immunotoxicology(影響因子:3.712)
發(fā)表時間:9 July 2022
作 者:Wang R, Zeng M, Zhang B, et al.
作者單位:河南中醫(yī)藥大學(xué)
使用產(chǎn)品:Rat TGF-β1 ELISA kit
https://pubmed.ncbi.nlm.nih.gov/35850599/
28.文章題目:Protective effects of di‐caffeoylquinic acids from Artemisia selengensis Turcz leaves against monosodium urate‐induced inflammation via the modulation of NLRP3 inflammasome and Nrf2 signaling pathway in THP‐1 macrophages.
期 刊:Journal of Food Biochemistry(影響因子:3.654)
發(fā)表時間:27 July 2022
作 者:Cao W, Wu T, Liang F, et al.
作者單位:華中農(nóng)業(yè)大學(xué)
使用產(chǎn)品:Human IL-18, IL-1β, TNF-α and IL-6 ELISA kits
https://pubmed.ncbi.nlm.nih.gov/35894102/
29.文章題目:Exosomes with FOXP3 from gene-modified dendritic cells ameliorate the development of EAE by regulating the balance of Th/Treg.
期 刊:Int J Med Sci(影響因子:3.462)
發(fā)表時間:1 July 2022
作 者:Jia Z, Liu J, Li B, et al.
作者單位:河北醫(yī)科大學(xué)第二醫(yī)院
使用產(chǎn)品:Mouse IFN-γ, IL-4, IL-6, IL-10and IL-17 ELISA kits
https://medsci.org/v19p1265.pdf
30.文章題目:WT1 Inhibits Human Renal Carcinoma Cell Proliferation and Induces G2/M Arrest by Upregulating IL-24 Expression.
期 刊:BioMed Research International(影響因子:3.246)
發(fā)表時間:8 July 2022
作 者:Jing Y J, Lin L C, Chen L L, et al.
作者單位:右江民族醫(yī)科大學(xué)
使用產(chǎn)品:Human IL-6 ELISA kit
https://www.hindawi.com/journals/bmri/2022/1093945/
31.文章題目:Astrocyte Activation, but not Microglia, Is Associated with the Experimental Mouse Model of Schizophrenia Induced by Chronic Ketamine.
期 刊:Journal of Molecular Neuroscience(影響因子:2.866)
發(fā)表時間:8 July 2022
作 者:Wei Y, Xiao L, Fan W, et al.
作者單位:四川大學(xué)
使用產(chǎn)品:Mouse IL-1β, IL-6, and TNF-α ELISA kit
樣本類型:海馬組織
https://pubmed.ncbi.nlm.nih.gov/35802289/
32.文章題目:A validated LC–MS/MS method for the determination of hederasaponin C: Application to Pharmacokinetic‐pharmacodynamic studies in the therapeutic area of acetic acid‐induced ulcerative colitis in rats.
期 刊:Biomedical Chromatography(影響因子:1.911)
發(fā)表時間:13 July 2022
作 者:Zhou B, Tian Y, Sun Y, et al.
作者單位:北京中醫(yī)藥大學(xué)
使用產(chǎn)品:Rat TNF-α, IL-6 and IL-1β ELISA kits
樣本類型:結(jié)腸組織
https://pubmed.ncbi.nlm.nih.gov/35831969/
33.文章題目:Decorin inhibits proliferation and metastasis in human bladder cancer cells by upregulating P21.
期 刊:Medicine(影響因子:1.817)
發(fā)表時間:1 July 2022
作 者:Chen H, Wang Z, Yang N, et al.
作者單位:甘肅蘭州市第一人民醫(yī)院
使用產(chǎn)品:Human TGF-β1 ELISA kit
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239591/
34.文章題目:Activation of GPR81 Aggravates Remote Organ Injury During Hepatic Ischemia-Reperfusion Injury.
期 刊:Transplantation Proceedings(影響因子:1.014)
發(fā)表時間:25 July 2022
作 者:Zan X, Fan K, Chen K, et al.
作者單位:重慶醫(yī)科大學(xué)
使用產(chǎn)品:Mouse TNF-α, IL-6 ELISA kits
https://pubmed.ncbi.nlm.nih.gov/35902290/
35.文章題目:The Application of PiCCO-guided Fluid Resuscitation in Patients With Traumatic Shock.
期 刊:The American Surgeon(影響因子:1.002)
發(fā)表時間:7 July 2022
作 者:Ni X, Liu X J, Ding T T.
作者單位:徐州醫(yī)科大學(xué)
使用產(chǎn)品:Human TNF-α ELISA kit
https://pubmed.ncbi.nlm.nih.gov/35797111/